Gao L, Zhuang J, Nie L, Zhang J, Zhang Y, Gu N, Wang T, Feng J, Yang D, Perrett S, Yan X. Intrinsic peroxidase-like exercise of ferromagnetic nanoparticles. Nat Nanotechnol. 2007;2:577–83.
Wei H, Wang E. Nanomaterials with enzyme-like traits (nanozymes): next-generation synthetic enzymes. Chem Soc Rev. 2013;42:6060–93.
Zandieh M, Liu J. Nanozymes: definition, exercise, and mechanisms. Adv Mater 2023:e2211041.
Shen X, Wang Z, Gao XJ, Gao X. Response mechanisms and kinetics of Nanozymes: insights from idea and computation. Adv Mater 2023:e2211151.
Chen Z, Yu Y, Gao Y, Zhu Z. Rational design methods for Nanozymes. ACS Nano. 2023;17:13062–80.
Nanozymology: connecting Biology and Nanotechnology. Singapore: Springer; 2020.
Wu J, Wang X, Wang Q, Lou Z, Li S, Zhu Y, Qin L, Wei H. Nanomaterials with enzyme-like traits (nanozymes): next-generation synthetic enzymes (II). Chem Soc Rev. 2019;48:1004–76.
Alizadeh N, Salimi A. Multienzymes exercise of metals and metallic oxide nanomaterials: functions from biotechnology to drugs and environmental engineering. J Nanobiotechnol. 2021;19:26.
Kandathil V, Patil SA. Single-atom nanozymes and environmental catalysis: a perspective. Adv Colloid Interface Sci. 2021;294:102485.
Shamsabadi A, Haghighi T, Carvalho S, Frenette LC, Stevens MM. The Nanozyme Revolution: enhancing the efficiency of Medical Biosensing platforms. Adv Mater 2023:e2300184.
Das B, Franco JL, Logan N, Balasubramanian P, Kim MI, Cao C. Nanozymes in Level-of-care analysis: an Rising Futuristic Method for Biosensing. Nanomicro Lett. 2021;13:193.
Hou H, Liu L, Li Q, Wang J, Du B. A Cascade enzyme system integrating peroxidase mimic with catalase for Linear Vary enlargement of H(2) O(2) assay: a mechanism and utility examine. Small. 2023;19:e2300444.
Zhang X, Chen X, Zhao Y. Nanozymes: versatile platforms for Most cancers analysis and remedy. Nanomicro Lett. 2022;14:95.
Sharma G, Chatterjee S, Chakraborty C, Kim JC. Advances in Nanozymes as a paradigm for viral Diagnostics and Remedy. Pharmacol Rev. 2023;75:739–57.
Navyatha B, Singh S, Nara S. AuPeroxidase nanozymes: guarantees and functions in biosensing. Biosens Bioelectron. 2021;175:112882.
Liu Q, Zhang A, Wang R, Zhang Q, Cui D. A overview on metal- and metallic oxide-based nanozymes: Properties, mechanisms, and functions. Nanomicro Lett. 2021;13:154.
Zhang S, Liu Y, Solar S, Wang J, Li Q, Yan R, Gao Y, Liu H, Liu S, Hao W, et al. Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for mind trauma. Theranostics. 2021;11:2806–21.
Xu W, Jiao L, Wu Y, Hu L, Gu W, Zhu C. Metallic-Natural frameworks Improve Biomimetic Cascade Catalysis for Biosensing. Adv Mater. 2021;33:e2005172.
Chen Y, Tian Q, Wang H, Ma R, Han R, Wang Y, Ge H, Ren Y, Yang R, Yang H et al. A manganese-based Metallic-Natural Framework as a Chilly-adapted Nanozyme. Adv Mater 2022:e2206421.
Gao W, He J, Chen L, Meng X, Ma Y, Cheng L, Tu Ok, Gao X, Liu C, Zhang M, et al. Deciphering the catalytic mechanism of superoxide dismutase exercise of carbon dot nanozyme. Nat Commun. 2023;14:160.
He Q, Zhang L. Design of carbon dots as nanozymes to mediate redox organic processes. J Mater Chem B. 2023;11:5071–82.
Zhuang J, Midgley AC, Wei Y, Liu Q, Kong D, Huang X. Machine-learning-assisted Nanozyme Design: classes from supplies and Engineered enzymes. Adv Mater 2023:e2210848.
Ren X, Chen D, Wang Y, Li H, Zhang Y, Chen H, Li X, Huo M. Nanozymes-recent improvement and biomedical functions. J Nanobiotechnol. 2022;20:92.
Yang B, Chen Y, Shi J. Reactive oxygen species (ROS)-Based mostly nanomedicine. Chem Rev. 2019;119:4881–985.
Singh N, Sherin GR, Mugesh G. Antioxidant and prooxidant nanozymes: from Mobile Redox Regulation to Subsequent-Technology therapeutics. Angew Chem Int Ed Engl. 2023;62:e202301232.
Halliwell B. Understanding mechanisms of antioxidant motion in well being and illness. Nat Rev Mol Cell Biol 2023.
Nathan C, Cunningham-Bussel A. Past oxidative stress: an immunologist’s information to reactive oxygen species. Nat Rev Immunol. 2013;13:349–61.
D’Autréaux B, Toledano MB. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol. 2007;8:813–24.
Cheung EC, Vousden KH. The position of ROS in tumour improvement and development. Nat Rev Most cancers. 2022;22:280–97.
Singh A, Kukreti R, Saso L, Kukreti S. Oxidative stress: a key modulator in neurodegenerative illnesses. Molecules 2019, 24.
Liu L, Zhang Ok, Sandoval H, Yamamoto S, Jaiswal M, Sanz E, Li Z, Hui J, Graham BH, Quintana A, Bellen HJ. Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration. Cell. 2015;160:177–90.
Zhang Y, Murugesan P, Huang Ok, Cai H. NADPH oxidases and oxidase crosstalk in cardiovascular illnesses: novel therapeutic targets. Nat Rev Cardiol. 2020;17:170–94.
Lei Y, Wang Ok, Deng L, Chen Y, Good EC, Huang C. Redox regulation of irritation: previous components, a brand new story. Med Res Rev. 2015;35:306–40.
Zhao H, Zhang R, Yan X, Fan Ok. Superoxide dismutase nanozymes: an rising star for anti-oxidation. J Mater Chem B. 2021;9:6939–57.
Xu D, Wu L, Yao H, Zhao L. Catalase-like Nanozymes: classification, Catalytic mechanisms, and their functions. Small. 2022;18:e2203400.
Lai Y, Wang J, Yue N, Zhang Q, Wu J, Qi W, Su R. Glutathione peroxidase-like nanozymes: mechanism, classification, and bioapplication. Biomater Sci. 2023;11:2292–316.
Jiang D, Ni D, Rosenkrans ZT, Huang P, Yan X, Cai W. Nanozyme: new horizons for responsive biomedical functions. Chem Soc Rev. 2019;48:3683–704.
Sheng Y, Abreu IA, Cabelli DE, Maroney MJ, Miller AF, Teixeira M, Valentine JS. Superoxide dismutases and superoxide reductases. Chem Rev. 2014;114:3854–918.
Islam MN, Rauf A, Fahad FI, Emran TB, Mitra S, Olatunde A, Shariati MA, Rebezov M, Rengasamy KRR, Mubarak MS. Superoxide dismutase: an up to date overview on its well being advantages and industrial functions. Crit Rev Meals Sci Nutr. 2022;62:7282–300.
Li H, Xia P, Pan S, Qi Z, Fu C, Yu Z, Kong W, Chang Y, Wang Ok, Wu D, Yang X. The advances of Ceria nanoparticles for Biomedical Functions in Orthopaedics. Int J Nanomed. 2020;15:7199–214.
Ma Y, Tian Z, Zhai W, Qu Y. Insights on catalytic mechanism of CeO(2) as a number of nanozymes. Nano Res. 2022;15:10328–42.
Kirkman HN, Gaetani GF. Mammalian catalase: a venerable enzyme with new mysteries. Tendencies Biochem Sci. 2007;32:44–50.
Alfonso-Prieto M, Biarnés X, Vidossich P, Rovira C. The molecular mechanism of the catalase response. J Am Chem Soc. 2009;131:11751–61.
Flohé L, Toppo S, Orian L. The glutathione peroxidase household: discoveries and mechanism. Free Radic Biol Med. 2022;187:113–22.
Flohé L, Loschen G, Günzler WA, Eichele E. Glutathione peroxidase, V. The kinetic mechanism. Hoppe Seylers Z Physiol Chem. 1972;353:987–99.
Zhang D, Shen N, Zhang J, Zhu J, Guo Y, Xu L. A novel nanozyme primarily based on selenopeptide-modified gold nanoparticles with a tunable glutathione peroxidase exercise. RSC Adv. 2020;10:8685–91.
Vernekar AA, Sinha D, Srivastava S, Paramasivam PU, D’Silva P, Mugesh G. An antioxidant nanozyme that uncovers the cytoprotective potential of Vanadia nanowires. Nat Commun. 2014;5:5301.
Wang Q, Liu J, He L, Liu S, Yang P. Nanozyme: a rising star for most cancers remedy. Nanoscale. 2023;15:12455–63.
Solar X, Xu X, Yue X, Wang T, Wang Z, Zhang C, Wang J. Nanozymes with Osteochondral Regenerative results: an summary of mechanisms and up to date functions. Adv Healthc Mater 2023:e2301924.
Glyn-Jones S, Palmer AJ, Agricola R, Worth AJ, Vincent TL, Weinans H, Carr AJ. Osteoarthritis. Lancet. 2015;386:376–87.
Yao Q, Wu X, Tao C, Gong W, Chen M, Qu M, Zhong Y, He T, Chen S, Xiao G. Osteoarthritis: pathogenic signaling pathways and therapeutic targets. Sign Transduct Goal Ther. 2023;8:56.
Lepetsos P, Papavassiliou AG. ROS/oxidative stress signaling in osteoarthritis. Biochim Biophys Acta. 2016;1862:576–91.
Lepetsos P, Papavassiliou KA, Papavassiliou AG. Redox and NF-κB signaling in osteoarthritis. Free Radic Biol Med. 2019;132:90–100.
Hou W, Ye C, Chen M, Gao W, Xie X, Wu J, Zhang Ok, Zhang W, Zheng Y, Cai X. Excavating bioactivities of nanozyme to transform microenvironment for shielding chondrocytes and delaying osteoarthritis. Bioact Mater. 2021;6:2439–51.
Xiong H, Zhao Y, Xu Q, Xie X, Wu J, Hu B, Chen S, Cai X, Zheng Y, Fan C. Biodegradable Hole-Structured Nanozymes modulate phenotypic polarization of macrophages and relieve hypoxia for therapy of Osteoarthritis. Small. 2022;18:e2203240.
Cho C, Oh H, Lee JS, Kang LJ, Oh EJ, Hwang Y, Kim SJ, Bae YS, Kim EJ, Kang HC, et al. Prussian blue nanozymes coated with Pluronic attenuate inflammatory osteoarthritis by blocking c-Jun N-terminal kinase phosphorylation. Biomaterials. 2023;297:122131.
Li Y, Yang J, Chen X, Hu H, Lan N, Zhao J, Zheng L. Mitochondrial-targeting and NIR-responsive mn(3)O(4)@PDA@Pd-SS31 nanozymes cut back oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis. Biomaterials. 2024;305:122449.
Zhou T, Ran J, Xu P, Shen L, He Y, Ye J, Wu L, Gao C. A hyaluronic acid/platelet-rich plasma hydrogel containing MnO(2) nanozymes effectively alleviates osteoarthritis in vivo. Carbohydr Polym. 2022;292:119667.
Wang W, Duan J, Ma W, Xia B, Liu F, Kong Y, Li B, Zhao H, Wang L, Li Ok, et al. Trimanganese Tetroxide Nanozyme protects cartilage towards degeneration by decreasing oxidative stress in Osteoarthritis. Adv Sci (Weinh). 2023;10:e2205859.
Yang X, Xiang J, Su W, Guo J, Deng J, Tang L, Li G, Liang Y, Zheng L, Zhong J et al. Modulating pt nanozyme through the use of remoted cobalt atoms to boost catalytic exercise for assuaging osteoarthritis. Nano In the present day 2023, 49.
Zhong J, Yang X, Gao S, Luo J, Xiang J, Li G, Liang Y, Tang L, Zheng L, Zhao J et al. Geometric and digital structure-matched Superoxide Dismutase-Like and Catalase-Like Sequential single-atom nanozymes for Osteoarthritis recession. Adv Funct Mater 2023, 33.
Xiang J, Yang X, Tan M, Guo J, Ye Y, Deng J, Huang Z, Wang H, Su W, Cheng J, et al. NIR-enhanced pt single atom/g-C(3)N(4) nanozymes as SOD/CAT mimics to rescue ATP vitality disaster by regulating oxidative phosphorylation pathway for delaying osteoarthritis development. Bioact Mater. 2024;36:1–13.
Wei H, Huang H, He H, Xiao Y, Chun L, Jin Z, Li H, Zheng L, Zhao J, Qin Z. Pt-Se Hybrid Nanozymes with Potent Catalytic actions to scavenge ROS/RONS and regulate macrophage polarization for Osteoarthritis Remedy. Res (Wash D C). 2024;7:0310.
Cai J, Liu LF, Qin Z, Liu S, Wang Y, Chen Z, Yao Y, Zheng L, Zhao J, Gao M. Pure morin-based metallic Natural Framework nanoenzymes modulate articular cavity microenvironment to Alleviate Osteoarthritis. Res (Wash D C). 2023;6:0068.
Yu B, Solar W, Lin J, Fan C, Wang C, Zhang Z, Wang Y, Tang Y, Lin Y, Zhou D. Utilizing Cu-Based mostly Metallic-Natural Framework as a Complete and highly effective antioxidant nanozyme for environment friendly osteoarthritis therapy. Adv Sci (Weinh). 2024;11:e2307798.
Hu H, Huang X, Dai Y, Zhu Ok, Ye X, Meng S, Zhang Q, Xie X. Natural metallic matrix Mil-88a nano-enzyme for joint restore within the osteoarthritis mouse mannequin. Entrance Bioeng Biotechnol. 2023;11:1164942.
Xu S, Mei X, Lin Y, Zhao X, Liang Z, Hu Y, Chen Z, Ren X. NIR triggered photocatalytic and photothermal bifunctional MOF nanozyme utilizing for enhancing osteoarthritis microenvironment by repairing injured chondrocytes of mitochondria. Chem Eng J 2023, 468.
Compston JE, McClung MR, Leslie WD. Osteoporosis. Lancet. 2019;393:364–76.
Wang L, Yu W, Yin X, Cui L, Tang S, Jiang N, Cui L, Zhao N, Lin Q, Chen L, et al. Prevalence of osteoporosis and fracture in China: the China osteoporosis prevalence examine. JAMA Netw Open. 2021;4:e2121106.
Clynes MA, Harvey NC, Curtis EM, Fuggle NR, Dennison EM, Cooper C. The epidemiology of osteoporosis. Br Med Bull. 2020;133:105–17.
Zhang C, Li H, Li J, Hu J, Yang Ok, Tao L. Oxidative stress: a standard pathological state in a high-risk inhabitants for osteoporosis. Biomed Pharmacother. 2023;163:114834.
Schröder Ok. NADPH oxidases in bone homeostasis and osteoporosis. Free Radic Biol Med. 2019;132:67–72.
Cheng C, Wentworth Ok, Shoback DM. New frontiers in osteoporosis remedy. Annu Rev Med. 2020;71:277–88.
Iantomasi T, Romagnoli C, Palmini G, Donati S, Falsetti I, Miglietta F, Aurilia C, Marini F, Giusti F, Brandi ML. Oxidative stress and irritation in osteoporosis: molecular mechanisms concerned and the connection with microRNAs. Int J Mol Sci 2023, 24.
Zheng L, Zhuang Z, Li Y, Shi T, Fu Ok, Yan W, Zhang L, Wang P, Li L, Jiang Q. Bone focusing on antioxidative nano-iron oxide for treating postmenopausal osteoporosis. Bioact Mater. 2022;14:250–61.
Ye C, Zhang W, Zhao Y, Zhang Ok, Hou W, Chen M, Lu J, Wu J, He R, Gao W, et al. Prussian Blue Nanozyme normalizes Microenvironment to Delay osteoporosis. Adv Healthc Mater. 2022;11:e2200787.
Li Ok, Huang J, Shi Y, Lin W, Liu X, Mao W, Wu C, Wang H, Chen H, Pan C et al. Focusing on ROS-induced osteoblast senescence and RANKL manufacturing by prussian blue nanozyme primarily based gene modifying platform to reverse osteoporosis. Nano In the present day 2023, 50.
Wei F, Neal CJ, Sakthivel TS, Fu Y, Omer M, Adhikary A, Ward S, Ta KM, Moxon S, Molinari M, et al. A novel strategy for the prevention of ionizing radiation-induced bone loss utilizing a designer multifunctional cerium oxide nanozyme. Bioact Mater. 2023;21:547–65.
Shao D, Li Ok, Hu T, Wang S, Xu H, Zhang S, Liu S, Xie Y, Zheng X. Titania nanotube array supported nanoceria with redox biking stability ameliorates oxidative stress-inhibited osteogenesis. Chem Eng J 2021, 415.
Li J, Chen Y, Zha D, Wu C, Li X, Yang L, Cao H, Cai S, Cai Y. Mg-ZIF nanozyme regulates the change between osteogenic and lipogenic differentiation in BMSCs through lipid metabolism. Lipids Well being Dis. 2024;23:88.
Francisco V, Pino J, González-Homosexual M, Lago F, Karppinen J, Tervonen O, Mobasheri A, Gualillo O. A brand new immunometabolic perspective of intervertebral disc degeneration. Nat Rev Rheumatol. 2022;18:47–60.
Vergroesen PP, Kingma I, Emanuel KS, Hoogendoorn RJ, Welting TJ, van Royen BJ, van Dieën JH, Smit TH. Mechanics and biology in intervertebral disc degeneration: a vicious circle. Osteoarthritis Cartilage. 2015;23:1057–70.
Wang F, Cai F, Shi R, Wang XH, Wu XT. Getting old and age associated stresses: a senescence mechanism of intervertebral disc degeneration. Osteoarthritis Cartilage. 2016;24:398–408.
Wang Y, Cheng H, Wang T, Zhang Ok, Zhang Y, Kang X. Oxidative stress in intervertebral disc degeneration: molecular mechanisms, pathogenesis and therapy. Cell Prolif. 2023;56:e13448.
Zhang HJ, Liao HY, Bai DY, Wang ZQ, Xie XW. MAPK /ERK signaling pathway: a possible goal for the therapy of intervertebral disc degeneration. Biomed Pharmacother. 2021;143:112170.
Zhou T, Yang X, Chen Z, Yang Y, Wang X, Cao X, Chen C, Han C, Tian H, Qin A, et al. Prussian blue nanoparticles stabilize SOD1 from Ubiquitination-Proteasome degradation to rescue intervertebral disc degeneration. Adv Sci (Weinh). 2022;9:e2105466.
Yang L, Yu C, Fan X, Zeng T, Yang W, Xia J, Wang J, Yao L, Hu C, Jin Y, et al. Twin-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration remedy. J Nanobiotechnol. 2022;20:433.
Shi Y, Li H, Chu D, Lin W, Wang X, Wu Y, Li Ok, Wang H, Li D, Xu Z, et al. Rescuing Nucleus Pulposus cells from Senescence through Twin-Useful Greigite Nanozyme to alleviate intervertebral disc degeneration. Adv Sci (Weinh). 2023;10:e2300988.
Shen J, Chen A, Cai Z, Chen Z, Cao R, Liu Z, Li Y, Hao J. Exhausted native lactate accumulation through injectable nanozyme-functionalized hydrogel microsphere for irritation aid and tissue regeneration. Bioact Mater. 2022;12:153–68.
Wu S, Shi Y, Jiang L, Bu W, Zhang Ok, Lin W, Pan C, Xu Z, Du J, Chen H, Wang H. N-Acetylcysteine-derived Carbon dots at no cost radical scavenging in intervertebral disc degeneration. Adv Healthc Mater. 2023;12:e2300533.
Salhotra A, Shah HN, Levi B, Longaker MT. Mechanisms of bone improvement and restore. Nat Rev Mol Cell Biol. 2020;21:696–711.
Bădilă AE, Rădulescu DM, Ilie A, Niculescu AG, Grumezescu AM, Rădulescu AR. Bone regeneration and oxidative stress: an up to date overview. Antioxid (Basel) 2022, 11.
Loi F, Córdova LA, Pajarinen J, Lin TH, Yao Z, Goodman SB. Irritation, fracture and bone restore. Bone. 2016;86:119–30.
Wei F, Neal CJ, Sakthivel TS, Kean T, Seal S, Coathup MJ. Multi-functional cerium oxide nanoparticles regulate irritation and improve osteogenesis. Mater Sci Eng C Mater Biol Appl. 2021;124:112041.
Li Ok, Xie Y, You M, Huang L, Zheng X. Cerium Oxide-Integrated Calcium Silicate Coating protects MC3T3-E1 osteoblastic cells from H(2)O(2)-Induced oxidative stress. Biol Hint Elem Res. 2016;174:198–207.
Yang S, Ji J, Luo M, Li H, Gao Z. Poly(tannic acid) nanocoating primarily based floor modification for building of multifunctional composite CeO(2)NZs to boost cell proliferation and antioxidative viability of preosteoblasts. Nanoscale. 2021;13:16349–61.
Pan H, Miao X, Deng J, Pan C, Cheng X, Wang X. Bimetallic Metallic-Natural Framework for Mitigating Aseptic Osteolysis. ACS Appl Mater Interfaces. 2023;15:4935–46.
Ahuja CS, Wilson JR, Nori S, Kotter MRN, Druschel C, Curt A, Fehlings MG. Traumatic spinal twine damage. Nat Rev Dis Primers. 2017;3:17018.
Hu X, Xu W, Ren Y, Wang Z, He X, Huang R, Ma B, Zhao J, Zhu R, Cheng L. Spinal twine damage: molecular mechanisms and therapeutic interventions. Sign Transduct Goal Ther. 2023;8:245.
Yu M, Wang Z, Wang D, Aierxi M, Ma Z, Wang Y. Oxidative stress following spinal twine damage: from molecular mechanisms to therapeutic targets. J Neurosci Res. 2023;101:1538–54.
Anjum A, Yazid MD, Fauzi Daud M, Idris J, Ng AMH, Selvi Naicker A, Ismail OHR, Athi Kumar RK, Lokanathan Y. Spinal twine Harm: pathophysiology, Multimolecular interactions, and underlying restoration mechanisms. Int J Mol Sci 2020, 21.
Kim JW, Mahapatra C, Hong JY, Kim MS, Leong KW, Kim HW, Hyun JK. Useful restoration of Contused spinal twine in rat with the injection of optimal-dosed Cerium Oxide nanoparticles. Adv Sci (Weinh). 2017;4:1700034.
Xu L, Mu J, Ma Z, Lin P, Xia F, Hu X, Wu J, Cao J, Liu S, Huang T, et al. Nanozyme-Built-in Thermoresponsive in situ forming Hydrogel enhances mesenchymal stem cell viability and paracrine impact for environment friendly spinal twine restore. ACS Appl Mater Interfaces. 2023;15:37193–204.
Xiong T, Yang Ok, Zhao T, Zhao H, Gao X, You Z, Fan C, Kang X, Yang W, Zhuang Y, et al. Multifunctional Built-in Nanozymes facilitate spinal twine regeneration by reworking the extrinsic neural atmosphere. Adv Sci (Weinh). 2023;10:e2205997.
Jiang Y, Rong H, Wang Y, Liu S, Xu P, Luo Z, Guo L, Zhu T, Rong H, Wang D, et al. Single-atom cobalt nanozymes promote spinal twine damage restoration by anti-oxidation and neuroprotection. Nano Res. 2023;16:9752–9.
Dalbeth N, Choi HK, Joosten LAB, Khanna PP, Matsuo H, Perez-Ruiz F, Stamp LK. Gout. Nat Rev Dis Primers. 2019;5:69.
Richette P, Bardin T. Gout. Lancet. 2010;375:318–28.
Stamp LK, Farquhar H. Remedy advances in gout. Finest Pract Res Clin Rheumatol. 2021;35:101719.
Schlesinger N, Pérez-Ruiz F, Lioté F. Mechanisms and rationale for uricase use in sufferers with gout. Nat Rev Rheumatol 2023.
Chen R, Yang J, Wu M, Zhao D, Yuan Z, Zeng L, Hu J, Zhang X, Wang T, Xu J, Zhang J. M2 macrophage hybrid membrane-camouflaged focused Biomimetic nanosomes to reprogram inflammatory microenvironment for enhanced enzyme-Thermo-Immunotherapy. Adv Mater. 2023;35:e2304123.
Ming J, Zhu T, Li J, Ye Z, Shi C, Guo Z, Wang J, Chen X, Zheng N. A Novel Cascade Nanoreactor integrating two-dimensional Pd-Ru Nanozyme, Uricase and Crimson Blood Cell membrane for extremely environment friendly hyperuricemia therapy. Small. 2021;17:e2103645.
Parmekar MV, Salker AV. Extremely tuned cobalt-doped MnO2 nanozyme as remarkably environment friendly uricase mimic. Appl Nanosci. 2020;10:317–28.
Liu D, Yang P, Wang F, Wang C, Chen L, Ye S, Dramou P, Chen J, He H. Research on efficiency of mimic uricase and its utility in enzyme-free evaluation. Anal Bioanal Chem. 2021;413:6571–80.
Liu D, Yi S, Ni X, Zhang J, Wang F, Yang P, Liu M, Peng J, Dramou P, He H. Preparation and Utility of Nanozymes with Uricase-Like Exercise primarily based on molecularly imprinted polymers. ChemPlusChem. 2023;88:e202200286.
Liu Y, Qin Y, Zhang Q, Zou W, Jin L, Guo R. Arginine-rich peptide/platinum hybrid colloid nanoparticle cluster: a single nanozyme mimicking multi-enzymatic cascade programs in peroxisome. J Colloid Interface Sci. 2021;600:37–48.
Lin A, Solar Z, Xu X, Zhao S, Li J, Solar H, Wang Q, Jiang Q, Wei H, Shi D. Self-Cascade Uricase/Catalase mimics alleviate Acute gout. Nano Lett. 2022;22:508–16.
Smith MH, Berman JR. What Is Rheumatoid Arthritis? Jama. 2022;327:1194.
McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med. 2011;365:2205–19.
Chen J, Zeng S, Xue Q, Hong Y, Liu L, Tune L, Fang C, Zhang H, Wang B, Sedgwick AC, et al. Photoacoustic image-guided biomimetic nanoparticles focusing on rheumatoid arthritis. Proc Natl Acad Sci U S A. 2022;119:e2213373119.
Jia M, Ren W, Liu Y, Wang C, Zheng X, Zhang D, Tan X, Li C. Messenger Nanozyme for Reprogramming the Microenvironment of Rheumatoid Arthritis. ACS Appl Mater Interfaces. 2023;15:338–53.
Zhao Y, Tune S, Wang D, Liu H, Zhang J, Li Z, Wang J, Ren X, Zhao Y. Nanozyme-reinforced hydrogel as a H(2)O(2)-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis remedy. Nat Commun. 2022;13:6758.
Kalashnikova I, Chung SJ, Nafiujjaman M, Hill ML, Siziba ME, Contag CH, Kim T. Ceria-based nanotheranostic agent for rheumatoid arthritis. Theranostics. 2020;10:11863–80.
Chen MW, Lu QJ, Chen YJ, Hou YK, Zou YM, Zhou Q, Zhang WH, Yuan LX, Chen JX. NIR-PTT/ROS-Scavenging/Oxygen-Enriched synergetic remedy for rheumatoid arthritis by a pH-Responsive hybrid CeO(2)-ZIF-8 coated with Polydopamine. ACS Biomater Sci Eng. 2022;8:3361–76.
Zhou F, Li M, Chen M, Chen M, Chen X, Luo Z, Cai Ok, Hu Y. Redox Homeostasis Technique for Inflammatory Macrophage Reprogramming in Rheumatoid Arthritis primarily based on Ceria Oxide Nanozyme-Complexed Biopolymeric Micelles. ACS Nano. 2023;17:4358–72.
Beird HC, Bielack SS, Flanagan AM, Gill J, Heymann D, Janeway KA, Livingston JA, Roberts RD, Strauss SJ, Gorlick R. Osteosarcoma. Nat Rev Dis Primers. 2022;8:77.
Gill J, Gorlick R. Advancing remedy for osteosarcoma. Nat Rev Clin Oncol. 2021;18:609–24.
Meltzer PS, Helman LJ. New Horizons within the Remedy of Osteosarcoma. N Engl J Med. 2021;385:2066–76.
Shoaib Z, Fan TM, Irudayaraj JMK. Osteosarcoma mechanobiology and therapeutic targets. Br J Pharmacol. 2022;179:201–17.
Du H, Zhang D, Xu R, Guan S, Chen S, Qian S, Liu X, Xie J, Peng F. Ferric oxide nanosheet-engineered mg alloy for synergetic osteosarcoma photothermal/chemodynamic remedy. J Mater Sci Technol. 2023;138:203–13.
Dong S, Lin Ok, Wang X, Chen Y, Yu L. Magnetic hyperthermia–synergistic H2O2 self-sufficient Catalytic suppression of Osteosarcoma with enhanced bone-regeneration bioactivity by 3D-Printing Composite scaffolds. Adv Funct Mater 2020, 30.
Wang L, Yang Q, Huo M, Lu D, Gao Y, Chen Y, Xu H. Engineering single-Atomic Iron-Catalyst-Built-in 3D-Printed Bioscaffolds for Osteosarcoma Destruction with Antibacterial and bone defect regeneration Bioactivity. Adv Mater. 2021;33:e2100150.
Liang Y, Liao C, Guo X, Li G, Yang X, Yu J, Zhong J, Xie Y, Zheng L, Zhao J. RhRu Alloy-Anchored MXene Nanozyme for Synergistic Osteosarcoma Remedy. Small. 2023;19:e2205511.
Masters EA, Ricciardi BF, Bentley KLM, Moriarty TF, Schwarz EM, Muthukrishnan G. Skeletal infections: microbial pathogenesis, immunity and scientific administration. Nat Rev Microbiol. 2022;20:385–400.
Hosseini Hooshiar M, Badkoobeh A, Kolahdouz S, Tadayonfard A, Mozaffari A, Nasiri Ok, Salari S, Safaralizadeh R, Yasamineh S. The potential use of nanozymes as an antibacterial brokers in oral an infection, periodontitis, and peri-implantitis. J Nanobiotechnol. 2024;22:207.
Qin L, Yang S, Zhao C, Yang J, Li F, Xu Z, Yang Y, Zhou H, Li Ok, Xiong C, et al. Prospects and challenges for the applying of tissue engineering applied sciences within the therapy of bone infections. Bone Res. 2024;12:28.
Xu Ok, Zou Y, Lin C, Zhang L, Tan M, Li M, Wu J, Li X, He Y, Liu P, et al. Cascade catalysis nanozyme for interfacial functionalization in combating implant infections related to diabetes through sonodynamic remedy and adaptive immune activation. Biomaterials. 2024;311:122649.
Gao Z, Tune Z, Guo R, Zhang M, Wu J, Pan M, Du Q, He Y, Wang X, Gao L, et al. Mn single-atom Nanozyme Functionalized 3D-Printed Bioceramic scaffolds for enhanced antibacterial exercise and bone regeneration. Adv Healthc Mater. 2024;13:e2303182.
Mei J, Xu D, Wang L, Kong L, Liu Q, Li Q, Zhang X, Su Z, Hu X, Zhu W, et al. Biofilm Microenvironment-Responsive Self-Meeting Nanoreactors for all-Stage Biofilm Related An infection via bacterial cuproptosis-like dying and macrophage re-rousing. Adv Mater. 2023;35:e2303432.
Zhu W, Mei J, Zhang X, Zhou J, Xu D, Su Z, Fang S, Wang J, Zhang X, Zhu C. Photothermal Nanozyme-based Microneedle Patch towards Refractory bacterial biofilm an infection through Iron-actuated Janus Ion Remedy. Adv Mater. 2022;34:e2207961.
Yang X, Xiang J, Su W, Guo J, Deng J, Tang L, Li G, Liang Y, Zheng L, He M et al. Modulating pt nanozyme through the use of remoted cobalt atoms to boost catalytic exercise for assuaging osteoarthritis. Nano In the present day 2023, 49.